Fapapcgene

由TYen著作·2022·被引用213次—FAPisacolorectalcancer(CRC)predispositionsyndromethatcanmanifestineitherclassicorattenuatedform.ClassicFAPischaracterizedbyhundredsto ...,Threevariantsareknowntoexist,FAPandattenuatedFAP(originallycalledhereditaryflatadenomasyndrome)arecausedbyAPCgenedefectsonchromosome5 ...,Understandinggenetictestresults.TherearedifferentAPCgenevariantsthatcauseFAP.Many,butnotall,...

參考資訊如下
APC-Associated Polyposis Conditions

由 T Yen 著作 · 2022 · 被引用 213 次 — FAP is a colorectal cancer (CRC) predisposition syndrome that can manifest in either classic or attenuated form. Classic FAP is characterized by hundreds to ...

Familial adenomatous polyposis

Three variants are known to exist, FAP and attenuated FAP (originally called hereditary flat adenoma syndrome) are caused by APC gene defects on chromosome 5 ...

Familial adenomatous polyposis (FAP)

Understanding genetic test results. There are different APC gene variants that cause FAP. Many, but not all, of them carry a very high risk of bowel cancer.

Familial adenomatous polyposis

2013年10月1日 — Familial adenomatous polyposis (FAP) is an inherited disorder characterized by cancer of the large intestine (colon) and rectum.

Familial adenomatous polyposis

Familial Adenomatous Polyposis

FAP is inherited in an autosomal dominant manner and caused by abnormalities (mutations) in the APC gene. Mutations in the APC gene cause a group of ...

The genetic basis of familial adenomatous polyposis and ...

由 ML Leoz 著作 · 2015 · 被引用 167 次 — Germline mutations in the APC gene are responsible for most cases of FAP. Individuals with a germline APC mutation develop multiple adenomas as ...